Cart
sales@molnova.com
Home - Products - Microbiology/Virology - Parasite - Chlorin E6

Chlorin E6

CAS No. 19660-77-6

Chlorin E6( —— )

Catalog No. M34843 CAS No. 19660-77-6

Chlorin E6 (CE6) is a second-generation photosensitizer with antitumor activity when used in combination with irradiation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 29 In Stock
25MG 40 In Stock
50MG 59 In Stock
100MG 95 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Chlorin E6
  • Note
    Research use only, not for human use.
  • Brief Description
    Chlorin E6 (CE6) is a second-generation photosensitizer with antitumor activity when used in combination with irradiation.
  • Description
    Chlorin e6 is a photosensitizer and has strong absorption peaks at wavelength of 402 and 662 nm, as well as exhibiting intense fluorescence at 668 nm. Chlorin e6 has antimicrobial efficacy and anticancer activity. Chlorin e6 induces cell apoptosis via caspase-3 activation and can be used for the research of cancer.
  • In Vitro
    Western Blot Analysis Cell Line:AsPC-1 and MIA PaCa-2 Cells Concentration:5 μM, 10 μM Incubation Time:3 h Result:Significantly reduced Bcl-2 protein expression while increasing apoptotic molecule expression of Bax.Activated caspase-3 through its cleavage and upregulated the expression of cleaved PARP-1 in a dose-dependent manner.
  • In Vivo
    Animal Model:B16F10 melanoma cells xenograft mouse, PANC02 pancreatic cells xenograft mouse Dosage:2.5 mg/kg Administration:Intravenous injection (i.v.)Result:Significantly reduced tumor volume.
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Parasite
  • Recptor
    Parasite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    19660-77-6
  • Formula Weight
    596.67
  • Molecular Formula
    C34H36N4O6
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 20.83 mg/mL (34.91 mM; Ultrasonic )
  • SMILES
    CCc1c(C)c2cc3[nH]c(cc4nc([C@@H](CCC(O)=O)[C@@H]4C)c(CC(O)=O)c4[nH]c(cc1n2)c(C)c4C(O)=O)c(C)c3C=C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Nie M, et al. Photodynamic inactivation mediated by methylene blue or chlorin e6 against Streptococcus mutans biofilm [J]. Photodiagnosis and photodynamic therapy, 2020, 31: 101817.?
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Naphthoquine phospha...

    An antimalarial drug.

  • Antitrypanosomal age...

    Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor (IC50: 3.3 μM).

  • D-Phenothrin

    D-Phenothrin is used in veterinary medicine to control pests on animals and to protect crops. D-Phenothrin is an orally effective type II synthetic pyrethroid widely used to kill insects, mosquitoes and human lice.

Sign In Join Free